
Mexico · Ciudad de México · Mexico City
Santa Fe, Mexico City — Area Guide & Where to Stay
Santa Fe is a modern business district in the west of Mexico City, built around Centro Santa Fe.
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Where to stay in Santa Fe
The practical side of choosing where to sleep.
Santa Fe keeps its beds among the towers. Most hotels rise on the corporate blocks near Centro Santa Fe, the largest mall in Latin America, so guests wake within reach of the offices, the shops, and the walking paths of Parque La Mexicana. Stay here for business and quiet mornings.
The southern side leans academic, its streets shaped by the Universidad Iberoamericana and the campus of Tecnológico de Monterrey, while the older edge toward Cuajimalpa holds a calmer residential grain. Avenida Vasco de Quiroga threads the whole district together.
Find hotels in Santa Fe
Direct booking searches for these neighbourhoods.
Around Centro Santa Fe
The core of the towers, where hotels sit steps from Centro Santa Fe and the green paths of Parque La Mexicana.Find hotels in Around Centro Santa Fecalmer nights near the campus streetsThe university edge
The southern grain of the district, shaped by the Universidad Iberoamericana and the campus of Tecnológico de Monterrey toward Cuajimalpa. Rooms are few around here — worth securing early.Find hotels in The university edgeHotel links are affiliate links: booking through them may earn us a commission, at no extra cost to you. It never affects how places are ranked. How this works
About Santa Fe
What are the main landmarks in Santa Fe?
Commerce sets the skyline here. Centro Santa Fe anchors the district as the largest mall in Latin America, and Parque La Mexicana carves an open green from the old quarried ground beside the office towers. Learning has a foothold too.
The Universidad Iberoamericana and the Santa Fe campus of Tecnológico de Monterrey draw students into the corporate grid, and the Universidad Panamericana keeps its own place among the western blocks, while Avenida Vasco de Quiroga carries traffic past the glass fronts toward Cuajimalpa.
What is the history of Santa Fe?
The name reaches back to 1532. Santa Fe carries the memory of Santa Fé de México, the pueblo hospital that Vasco de Quiroga founded on the western slopes above Mexico City. Sand mines came later.
Through the middle of the last century the quarries were dug out and then filled as a dump, until the pits were levelled and the ground reborn as a business district, its skyline crowded with towers around Centro Santa Fe and its slopes softened by the lawns of Parque La Mexicana. The Universidad Iberoamericana arrived in 1982 and set the academic tone.
Where is Santa Fe?
Santa Fe spreads across the western hills of Mexico City, straddling the boroughs of Cuajimalpa and Álvaro Obregón, its towers set on ground once quarried for sand.
Common questions
What is the best area to stay in Santa Fe?
Around Centro Santa Fe: corporate stays beside the largest mall in Latin America. The university edge: calmer nights near the campus streets.
More areas in Mexico City
Updated October 2026




