United States · Missouri · St. Louis
Midtown St. Louis, St. Louis — Area Guide & Where to Stay
Midtown St. Louis holds Saint Louis University and the arts blocks along Grand Boulevard, three miles west of the city riverfront.
About Midtown St. Louis
Where to stay in Midtown St. Louis
Where you base yourself shapes the visit — here's the character of each area.
Grand Boulevard sets the choice. Rooms sit close to the Saint Louis University campus, which puts the Saint Louis University Museum of Art and the Contemporary Art Museum St. Louis within a short walk of most doors.
Lindell Boulevard carries the quieter blocks. A downtown room means the three miles back east to the riverfront.
About Midtown St. Louis
What are the main landmarks in Midtown St. Louis?
The Pulitzer Foundation for the Arts and the Contemporary Art Museum St. Louis anchor the Grand Boulevard arts blocks, and Saint Louis University adds two of its own. They are the Saint Louis University Museum of Art and the Museum of Contemporary Religious Art. St. Francis Xavier College Church fronts Grand Boulevard at the campus edge.
The Desloge Chapel stands close behind. The Scott Joplin House State Historic Site preserves a ragtime composer's rooms a short way off.
What is the history of Midtown St. Louis?
Saint Louis University sets the age of these blocks. Its lecture halls and its College Church stand on either side of Grand Boulevard, and the campus has held that ground while galleries and museums gathered around it. Older congregations left their own marks: St. Alphonsus Catholic Church, the Immaculate Conception Church and Rectory, and the Second Presbyterian Church.
The Desloge Chapel joins them. Much later the Pulitzer Foundation for the Arts took a Grand Boulevard address.
Where is Midtown St. Louis?
The crossing of Grand Boulevard and Lindell Boulevard fixes Midtown's centre, with the Saint Louis University campus spreading south and the riverfront three miles east.
Good for
More areas in St. Louis
Updated September 2026