United States · Missouri · St. Louis
Mount Pleasant, St. Louis — Area Guide & Where to Stay
Mount Pleasant slopes to the Mississippi River in south St. Louis, holding Sugarloaf Mound, the last intact Native American mound inside the city.
About Mount Pleasant
Where to stay in Mount Pleasant
Where you base yourself shapes the visit — here's the character of each area.
Virginia Avenue and Meramec Street are the two commercial corridors, and the storefronts along them run to taverns and parish halls rather than lobbies. Rooms sit downtown. Interstate 55 slices the eastern edge, so the drive in takes minutes, and South Broadway feeds the same ground from the north.
You want brick two-flats and a river bluff, not a lobby.
About Mount Pleasant
What are the main landmarks in Mount Pleasant?
Sugarloaf Mound rises over Ohio Avenue. Mississippian builders raised the terraced earthwork long before Europeans reached the confluence, and it is the last intact Native American mound left inside the St. Louis city limits, held since 2009 by the Osage Nation. St. Anthony of Padua Church anchors the Meramec Street edge, and Franciscans have kept the parish there for generations.
Mount Pleasant Park takes the rest of the attention, and an outdoor roller hockey rink fills its southwest corner beside the playground equipment.
What is the history of Mount Pleasant?
Carondelet governed itself to the south until annexation in 1870. Sugarloaf Mound stood on that municipal line. Maryville University opened as a Sacred Heart boarding school at Meramec and Nebraska in 1872, and the order held the campus until the move to Town and Country in 1961.
Duchesne Hall carried murals of the foundress, Rose Philippine Duchesne. Fire and demolition ended it in 1973. Maryville Gardens went up on the ground instead.
Where is Mount Pleasant?
Streets draw three edges. Compton Avenue runs west, Meramec Street north and Eichelberger Street south, and the Mississippi River closes the east below the bluff.
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Updated September 2026