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Low-rise tree-lined neighborhood with scattered towers in the Palermo area of Buenos Aires

Argentina · Ciudad Autónoma de Buenos Aires · Buenos Aires

Palermo Soho, Buenos Aires — Area Guide & Where to Stay

Palermo Soho is a design-led quarter of Palermo, the largest barrio of Buenos Aires.

About Palermo Soho

Where to stay in Palermo Soho

The right area depends on your trip — here's what each neighbourhood is best for.

Palermo Soho carries beds of its own. As a design quarter of Palermo, it puts small hotels and guesthouses within walking reach of galleries, restaurants and the Basílica del Espíritu Santo, a short hop from the rest of Buenos Aires by the avenues that ring it. Base yourself here for the streets.

The wider barrio spreads beyond.

About Palermo Soho

What are the main landmarks in Palermo Soho?

Palermo Soho keeps churches of three traditions. The Basílica del Espíritu Santo anchors one plaza, while the Saint George Antiochian Orthodox Cathedral rises along Avenida Scalabrini Ortiz and the Armenian Saint Gregory the Illuminator Cathedral serves the community that settled this corner of Palermo. Spires mark the skyline.

Between them the streets fill with galleries, design studios and cafés.

What is the history of Palermo Soho?

Palermo Soho grew out of the old Palermo Viejo core. The quarter took shape as low houses and workshops filled the blocks of Palermo, later drawing design studios and galleries that gave the streets around the Basílica del Espíritu Santo their present cast within Buenos Aires. Immigrant congregations left their mark.

Armenian and Orthodox families raised churches here.

Where is Palermo Soho?

Palermo Soho occupies the low-rise heart of Palermo. The quarter fills a grid of leafy streets and cobbled corners inside the wider Palermo barrio, set back from the Río de la Plata that edges the northern reach of Buenos Aires, with Avenida Scalabrini Ortiz drawing one of its outer lines. The river lies to the north.

Flat ground carries the streets.

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More areas in Buenos Aires

Updated July 2026