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Mark Twain/I-70 Industrial, St. Louis — Area Guide & Where to Stay

Interstate 70 runs the north edge of Mark Twain/I-70 Industrial, a warehouse quarter of northwest St. Louis, Missouri, off the Goodfellow Boulevard exit.

About Mark Twain/I-70 Industrial

Where to stay in Mark Twain/I-70 Industrial

Not every neighbourhood fits every trip — here's what each one is good for.

Mark Twain/I-70 Industrial is working ground, and its name says so. Warehousing covers the old General Motors truck plant on Union Boulevard, and the rooms for any visit here are booked somewhere else in St. Louis.

Exit 243A is the way in. That ramp lands on Goodfellow Boulevard, exit 244A lands on Union Boulevard, and Interstate 70 runs from either one toward the middle of the city. Mark Twain begins across North Kingshighway, Kingsway West across Natural Bridge Road.

Choose a downtown room if warehouse ground and old plant sites are what you came for.

About Mark Twain/I-70 Industrial

What are the main landmarks in Mark Twain/I-70 Industrial?

The one set piece in Mark Twain/I-70 Industrial is the Union Seventy Center, a distribution campus of 161 acres laid over the General Motors plant that assembled trucks, B-body sedans, and the Corvette on Union Boulevard before it closed in 1986. Its main building keeps the old assembly hall, 2.2 million square feet of it. Goodfellow Boulevard carries the rest.

The Army's records centre stood at 4300 Goodfellow Boulevard in a converted wartime cartridge works, and that building was pulled down in 2006. No address in the neighbourhood holds a National Register listing.

What is the history of Mark Twain/I-70 Industrial?

Mark Twain/I-70 Industrial was the arsenal end of wartime St. Louis. The U.S. Cartridge Company ran the city's largest war plant at Goodfellow Boulevard and Bircher Boulevard, turning out more than a billion rounds a year, and in September 1945 the Army took the buildings for a records centre holding the files of discharged soldiers.

The records work moved out in 1956. General Motors came earlier. A Fisher body and Chevrolet chassis plant opened on Union Boulevard in the 1920s, built DUKW amphibious trucks during the war, and assembled every Corvette made between 1954 and 1981.

Where is Mark Twain/I-70 Industrial?

Interstate 70 draws the north line of Mark Twain/I-70 Industrial, North Kingshighway the east, Natural Bridge Road the south, and the St. Louis city limit the west.

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Updated September 2026